Agranulocytosis during treatment of chronic hepatitis C complicated by hyperthyreosis. Case reports.
نویسندگان
چکیده
Agranulocytosis is a life-threatening disorder characterised by a greatly decreased number of circulating neutrophils below 500/μL. This article presents two cases of agranulocytosis in patients treated with pegylated interferon and ribavirin due to chronic hepatitis C. Interferon induced hyperthyroidism, which required the use of a tyreostatic. Anti-thyroid drugs (ATD) used to treat hyperthyroidism can cause agranulocytosis. The synergistic reaction of ATD and interferon on bone marrow cannot be excluded.
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ورودعنوان ژورنال:
- Endokrynologia Polska
دوره 63 1 شماره
صفحات -
تاریخ انتشار 2012